What Side Effects Can Antidepressants Trigger?
Different antidepressants come with various side effects, ranging from common to rare. You may or may not experience these, and some may diminish over time.
Before deciding if an antidepressant is right for you, consult your doctor.
Common Side Effects by Antidepressant Type
Here are common to rare side effects for each category :
SSRIs and SNRIs
- Lowered alertness
- Headaches
- Nausea
- Sexual issues
- Oral health concerns
- Diabetes
- SIADH
- Gut bleeding
- Serotonin syndrome
- Suicidal tendencies
- Neuroleptic malignant syndrome
- Hypomania or mania
Tricyclics
- Antimuscarinic effects
- Oral health issues
- Lowered alertness
- Suicidal tendencies
- SIADH
- Diabetes
- Neuroleptic malignant syndrome
- Hypomania or mania
MAOIs
- Reduced alertness
- SIADH
- Serotonin syndrome
- Diabetes
- Suicidal tendencies
- Neuroleptic malignant syndrome
How Do These Side Effects Affect Me?
Antimuscarinic Effects
These stem from altered acetylcholine levels and can include blurred vision, constipation, dry mouth, and rapid heartbeat, among others.
Lowered Alertness
This may impair your ability to drive or perform skilled tasks, especially when you first start medication.
Diabetes
Prolonged use of SSRIs or tricyclics can increase diabetes risk, particularly for those over 30.
Gut Bleeding
Rare but more likely in those over 80, causing doctors to recommend alternative medications.
Hypomania or Mania
Could indicate bipolar disorder and may necessitate a medication switch.
Neuroleptic Malignant Syndrome
A rare, severe neurological disorder with symptoms like high temperature and tremors, requiring immediate medical attention.
Serotonin Syndrome
Rare but serious; symptoms include headaches, high temperature, and high blood pressure.
Sexual Issues
Varied and can include delayed or spontaneous orgasms and reduced libido.
SIADH
A rare, fatal condition causing low sodium levels, resulting in symptoms like confusion and hallucinations.
Suicidal Feelings
Particularly associated with SSRIs; if experienced, seek immediate medical help.
Oral Health
Long-term use of drugs causing dry mouth can lead to tooth decay.